Cultural shift throughout Europe has led to the Christian worldview and Judeo-Christian values being jettisoned and a secular humanist worldview and values increasingly imposed. The toxic cocktail of scientific materialism, consumerism, moral relativism and radical autonomy, in denying the authority of the Bible and the principle of imago dei has opened the lid of a Pandora’s box of new biotechnologies and propelled us to a path embracing abortion, embryo research and euthanasia. In responding to this Christians need to be able first to critique secular ethical frameworks based on duties (Kant), consequences (Mill) and virtues (Plato), identifying their strengths and weaknesses. Next, we need to develop and articulate a genuinely evangelical framework earthed in biblical principles, duties and outcomes and rooted in the character of God.