Various lines of genomic evidence support the biological relatedness of all life on Earth. It is commonly thought that this claim undermines a theistic account of biological origins, and perhaps particularly a Christian one. One strand of this objection is that common descent undermines natural theological arguments from biology. In this talk I will focus on unpacking some of the genomic evidence, explaining data which I believe all accounts should attempt to deal with. I will also briefly outline some possible routes for theistic 'bio-theological' arguments.